Yeah,
Internet hotspotting will lead to crowded boat ramps, and educated fish that snub their nose at artificials...or fish that wind up in parking lot photos on their way to the cutting board.
The Noli has some nice muskies, but it has so much habitat for them to spread around, so they can be very elusive. Plus the darned river stays so murked up for weeks, that it leaves very narrow windows for spotting following fish. I have fished more hours for less return on the Noli than any other musky river; therefore, I often make the long drives to mid TN, VA, NC, and WV to fish for them, where I know I'll have several more opportunities for a caught fish.
The rocky shoals in that river make jetboating a bumpy ride, I'd recommend finding a good welder and an extra jet foot. Rafts or small jons/canoes with muddy bank put-ins or long floats will get you more effectively to some great looking water.
If you manage to find a good holding spot with a couple big fish hangin around, keep it to yourself and trusted friends, because there are several tenacious musky chasers (like me) who will find them and fish them regularly. Nowadays it's become quite a craze to post internet photos with backgrounds and YOUTUBE videos of fish being caught.
I have found some nice honey holes just because someone captured a revealing landmark in the background. (Thanks to Google Earth)
Your standard musky gear and lures will work on that river, and yes, there are some hard to find hogs.
Good luck